A recent study by researchers at Columbia University reveals that chlorthalidone, a common medication for high blood pressure, carries a higher risk of serious side effects compared to hydrochlorothiazide.
A recent study from Columbia University has raised concerns about the safety of chlorthalidone, a popular medication used to treat high blood pressure. The 17-year study, which followed over 730,000 patients, found that chlorthalidone was linked to a higher risk of serious side effects compared to hydrochlorothiazide, another blood pressure medication. The study revealed that 6.3% of patients on chlorthalidone developed hypokalemia, a dangerous condition caused by low potassium levels, while only 1.9% of those on hydrochlorothiazide were affected. The study also highlighted a higher risk of kidney issues and electrolyte imbalances in chlorthalidone users, even at low doses.
The findings challenge the long-standing use of chlorthalidone as a first-line treatment for hypertension. Experts suggest that doctors should monitor patients more closely when prescribing chlorthalidone and may consider alternative treatments with fewer risks.