US making COVID antiviral drug more available at test sites

AP

WASHINGTON — The White House on Thursday announced more steps to make the antiviral treatment Paxlovid more accessible across the U.S. as it projects COVID-19 infections will continue to spread over the summer travel season.

The nation’s first federally backed test-to-treat site is opening Thursday in Rhode Island, providing patients with immediate access to the drug once they test positive. More federally supported sites are set to open in the coming weeks in Massachusetts and New York City, both hit by a marked rise in infections.

Next week, the U.S. will send authorized federal prescribers to several Minnesota-run testing sites, turning them into test-to-treat locations. Federal regulators have also sent clearer guidance to physicians to help them determine how to manage Paxlovid’s interactions with other drugs, with an eye toward helping prescribers find ways to get the life-saving medication to more patients.

Despite a nationwide surge in COVID-19 cases, deaths from the virus have remained largely stable over the past eight weeks, as vaccine booster shots and widely accessible treatments have helped to delink infections and mortality.

Confirmed infections in the U.S. have quadrupled since late March, from about 25,000 a day to more than 105,000 daily now. But deaths, which have tended to lag infections by three to four weeks over the course of the coronavirus pandemic, have declined steadily and are now plateaued at fewer than 300 per day.

It’s the first time in the course of the pandemic that the two have not trended together, said White House COVID-19 coordinator Dr. Ashish Jha. He called it an important development in helping Americans get back to normal life.

“What has been remarkable in the latest increase in infections we’re seeing is how steady serious illness and particularly deaths are eight weeks into this,” he said. “COVID is no longer the killer that it was even a year ago.”

Jha said that given the wider use of at-home rapid tests, whose results often go unreported to public health officials, the true number of daily infections is likely 200,000 or more — double the reported rate — which he said only makes the death rate plateau more significant.

He credited vaccines but also a more than four-fold increase in prescriptions over the last six weeks for the highly effective treatment Paxlovid.

Jha said about 25,000 to 30,000 courses of Paxlovid are being prescribed each day. When administered within five days of symptoms appearing, the drug has been proven to bring about a 90% reduction in hospitalizations and deaths among patients most likely to get severe disease.